The MUA Library

Includes bibliographical references and index.

Approaches used by others and existing safety frameworks -- The framework -- Categories of scientific evidence--human information and data -- Categories of scientific evidence--animal data -- Categories of scientific evidence--information about related substances -- Categories of scientific evidence--in vitro data -- Interactions -- Vulnerable groups and prevalence of use -- Scientific principles for integrating and evaluating the available data -- Applying the framework: case studies using the prototype safety monographs -- Factors influencing use of the safety framework -- Findings and recommendations.